Woman was created out of one of Adam’s ribs:

Genesis 2:21-22
And the Lord God caused a deep sleep to fall upon Adam, and he slept: and he took one of his ribs, and closed up the flesh instead thereof;

And the rib, which the Lord God had taken from man, made he a woman, and brought her unto the man.

Prior to the tower of babel, there was only one language and one accent on earth:

Genesis 11:1
And the whole earth was of one language, and of one speech.

One blood, one earth ~ thus, no aliens or reptilians and no habitation in outer space:

Acts 17:26
And hath made of one blood all nations of men for to dwell on all the face of the earth, and hath determined the times before appointed, and the bounds of their habitation;

There is only one God:

Romans 3:30
Seeing it is one God, which shall justify the circumcision by faith, and uncircumcision through faith.

By one man sin/death entered the world:

Romans 5:12
Wherefore, as by one man sin entered into the world, and death by sin; and so death passed upon all men, for that all have sinned:

And by the righteousness of one Man the free gift of salvation/life came upon all men:

Romans 5:18
Therefore as by the offence of one judgment came upon all men to condemnation; even so by the righteousness of one the free gift came upon all men unto justification of life.

There is one body of believers:

Romans 12:4-5
For as we have many members in one body, and all members have not the same office: So we, being many, are one body in Christ, and every one members one of another.

Who should glorify God having one mind and one mouth:

Romans 15:6
That ye may with one mind and one mouth glorify God, even the Father of our Lord Jesus Christ.

Joined to the Lord with one spirit:

1 Corinthians 6:17
But he that is joined unto the Lord is one spirit.

In future, He will gather together both the earthly and the heavenly in one at a future allotted time:

Ephesians 1:10
That in the dispensation of the fulness of times he might gather together in one all things in Christ, both which are in heaven, and which are on earth; even in him:

The body of Christ, otherwise known as the one new man:

Ephesians 2:15
Having abolished in his flesh the enmity, even the law of commandments contained in ordinances; for to make in himself of twain one new man, so making peace;

We have access to the Father through one Spirit:

Ephesians 2:18
For through him we both have access by

one Spirit unto the Father.

One hope,

Ephesians 4:4-6
There is one body, one Spirit, one Lord, one faith, one baptism & One God:

and one Spirit, even as ye are called

in one hope of your calling;

One Lord,

one faith,

one baptism,

One God and Father of all, who is above all, and through all, and in you all.

One God and one mediator:

1 Timothy 2:5-6
For there is one God, and one mediator between God and men, the man Christ Jesus;

Who gave himself a ransom for all, to be testified in due time.

Thus, no Mohammeds, no Buddhas, or Mahdis can be elected as intermediaries between God and Man.